Medical injection device packaging

ABSTRACT

Packaging for an injection device, the packaging including a channel extending longitudinally to accommodate the injection device, the channel including a longitudinal wall adjoining a base wall; a handling recess extending laterally and formed through the longitudinal wall, a positioning rib extending longitudinally and protruding from the base wall into the channel for insertion into a positioning recess of the injection device, the positioning rib arranged offset laterally from the recess and extending in a longitudinal field defined by the handling recess.

CROSS-REFERENCE TO RELATED APPLICATION

This application claims the benefit of Great Britain Patent ApplicationNo. 1621275.5 filed on Dec. 14, 2016, the disclosure of which isincorporated herein by reference in its entirety.

TECHNICAL FIELD

The present disclosure relates generally to the field of medicalpackaging for containing medical injection devices and in particularmedical tray type packaging for containing said devices.

BACKGROUND

Medical tray type packaging of the type for containing a medicalinjection device commonly comprises a thermoformed tray formed from aplastic sheet. The plastic sheet is formed to extend around the device.To close the tray a tear away or break through lid may be provided asmedical blister type packaging. Alternatively, the lid formed of acorresponding plastic sheet may be arranged as medical clamshell typepackaging.

Medical tray type packaging may differ from traditional pharmaceuticalblister packaging for unit-dose packaging of tablets in that, forprotection of the device, the tray is not collapsible. The devicetherefore cannot be pushed-though for extraction. Consequently, aprocess for extraction of a device from a tray can be more complex. Itmay comprise removal/perforation of the lid and a user reaching intopart of the channel and gripping the device. The channel may be narrowand difficult to access, particularly for users who have and illnessreducing their dexterity.

In spite of the effort already invested in the development of saidpackaging, further improvements are desirable.

BRIEF DESCRIPTION OF THE FIGURES

Aspects, features and advantages of embodiments of the presentdisclosure will become apparent from the following description ofembodiments in reference to the appended drawings in which like numeralsdenote like elements.

FIG. 1 is an exploded schematic perspective diagram showing anembodiment packaging and an embodiment injection device, wherein apositioning recess of the injection device is shown in hidden line.

FIG. 2 is a side schematic diagram showing the embodiment packaging ofFIG. 1 accommodating the injection device of FIG. 1 , wherein theinjection device is shown in hidden line.

FIG. 3 is a plan schematic diagram showing embodiments of the packagingof FIG. 1 .

FIG. 4 is a plan view showing a planform of embodiment packaging.

FIG. 5 is a side view showing the embodiment packaging of FIG. 4 .

FIG. 6 is a front sectional view showing the embodiment packaging ofFIG. 4 .

FIG. 7 is a perspective view showing the embodiment packaging of FIG. 4.

FIG. 8 is a front sectional view showing an embodiment positioning ribof the packaging accommodated in an embodiment positioning recess of anembodiment injection device.

FIG. 9 is a front sectional view showing an embodiment positioning ribof the packaging accommodated in an embodiment positioning recess of anembodiment injection device.

FIG. 10 is a front sectional view showing an embodiment positioning ribof packaging accommodated in an embodiment positioning recess of anembodiment injection device.

FIG. 11 is a side sectional view showing an embodiment positioning ribof the packaging accommodated in an embodiment positioning recess of anembodiment injection device.

FIGS. 12 and 13 are perspective views showing a portion of theembodiment packaging of FIG. 4 .

FIG. 14 is a perspective cut-away view showing abutment between stackedpackaging of the embodiment packaging of FIG. 4 and an injection deviceaccommodated in the packaging.

FIG. 15 is a perspective cut away view showing stacked packagingextending in a longitudinal direction, the packaging of the embodimentpackaging of FIG. 4 .

FIG. 16 is a perspective cut away view showing a peripheral lateral wallof stacked packaging, the packaging of the embodiment packaging of FIG.4 .

FIG. 17 is a perspective view showing stacked packaging, the packagingof the embodiment packaging of FIG. 4 .

DETAILED DESCRIPTION OF EMBODIMENTS

Before describing embodiments of the packaging, it is to be understoodthat the packing is not limited to the details of construction orprocess steps set forth in the following description. It will beapparent to those skilled in the art having the benefit of the presentdisclosure that the packaging is capable of other embodiments and ofbeing practiced or being carried out in various ways.

Accordingly, the embodiments are merely examples and should not beconstrued to narrow the scope or spirit of the subject matter describedherein in any way. Moreover, the embodiments may be combined in anysuitable combination to provide further embodiments.

The present disclosure may be better understood in view of the followingexplanations:

As used herein, the terms “package” or “packaging” may encompass anyarrangement to wrap or protect an injection device. Packaging can berigid or flexible. Packaging may include blister packs, medicalclamshell, clamshell trays, medical trays and other like arrangements.The packaging may be sterile or nonsterile.

As used herein, the term “injection device” may include a device for theinjection of a medicament to a body of a human or animal subject andincludes devices configured for various delivery methods, such asintradermal, subcutaneous, intramuscular, intravenous, intraosseous,intraperitoneal, intrathecal, epidural, intracardiac, intraarticular,intracavernous, intravitreal or other like method. Injection deviceincludes syringes of all types, devices that contain said syringes suchas auto-injectors, pen-injectors and other like devices.

As used herein, the term “auto-injector” may include any deviceconfigured to deliver a dose of a medicament from a prefilled syringe.The auto-injector may be configured to deliver a single dose of amedicament. Auto-injectors may include a device comprising a prefilledsyringe that contains a medicament. The prefilled syringe may beembedded in the auto-injector, for example for a disposable device. Inother embodiments, the prefilled syringe may be insertable in andremovable from the auto-injector, for example for a multi-use device.The syringe may be spring, gas or otherwise actuated for said delivery.A presently available example is the DAI™ by SHL Group and the Ypsomate™by Ypsomed.

As used herein, the term “pen-injector” may include any deviceconfigured to deliver a dose of a medicament from a cartridge. Thedelivery may be via spring, gas or otherwise actuated.

As used herein, the terms “grip” or “gripping” may include to hold byclasping or grasping with digits of hands of a user with a pincer typeaction. Grip includes a manner of gripping suitable for removing aninjection device as defined herein from a channel as defined herein.Grip includes a user's opposed digits pressing against the injectiondevice such that frictional forces are greater that the weight of theinjection device or the force retaining the injection device in thechannel.

The term “digits” may include reference to one or two fingers and anopposed thumb. The fingers are typically selected from the index finger,middle finger, ring finger. The size of user's fingers and thumb arewithin conventionally accepted ranges. In an example, user fingers andthumbs may be idealised as having a hemispherical tip that extends intoa nominal circular cross-sectioned body. For fingers the body may have adiameter that may be 10-20 mm. For thumbs the body may have a diameterthat may be 10-30 mm. Further hand dimensions may be as defined byhttp://usability.gtri.gatech.edu/eou_info/hand_anthro.php or similarhand/finger anthropometry study.

As used herein “user” is intended to refer to a healthcare professional,a medical practitioner, human end user or other human user associatedtherewith.

As used herein, the term “medicament” may include a substance, which maybe in liquid form. The medicament can include a substance for use in thetreatment or prevention of a disorder that causes reduced dexterity of auser, examples include multiple sclerosis, rheumatoid arthritis,muscular atrophy, Parkinson's disease, celiac disease, Alzheimer'sdisease.

In an embodiment medicament comprises Glatiramer acetate (GA). GA is amixture of polypeptides which do not all have the same amino acidsequence GA is marketed under the tradename Copaxone®. GA comprises theacetate salts of polypeptides containing L-glutamic acid, L-alanine,L-tyrosine and L-lysine at average molar fractions of 0.141, 0.427,0.095 and 0.338, respectively. The average molecular weight of Copaxone®is between 5,000 and 9,000 daltons. (“Copaxone”, Physician's DeskReference, (2005), Medical Economics Co., Inc., (Montvale, N.J.), 3115.)Chemically, glatiramer acetate is designated L-glutamic acid polymerwith L-alanine, L-lysine, L-tyrosine, acetate (salt).

In an embodiment medicament comprises an anti-TNFα antibody, preferablythe anti-TNFα antibody is adalimumab. Adalimumab is marketed under thetrade name Humira® and is described in U.S. Pat. No. 6,090,382.

In an embodiment the medicament comprises Follicle-stimulating hormone(FSH), also known as follitropin alfa. FHS is for the treatment ofinfertility. FSH is marketed under the following brands: Ovaleap® (TevaPharma); Gonal-f® (Merck Serono); Puregon (Merck Sharp and Dohme),Bemfola (Finox Biotech), Elonva (Merck Sharp and Dohme). FSH is for usein the treatment of the following indications: anovulation (includingpolycystic ovarian syndrome) in women who have been unresponsive totreatment with clomifene citrate; stimulation of multifolliculardevelopment in women undergoing superovulation for assisted reproductivetechnologies (ART) such as in vitro fertilisation (IVF), gameteintra-fallopian transfer and zygote intra-fallopian transfer; FSH inassociation with a luteinising hormone (LH) preparation is for thestimulation of follicular development in women with severe LH and FSHdeficiency, in clinical trials these patients were defined by anendogenous serum LH level <1.2 IU/L; FSH is for use in the stimulationof spermatogenesis in men who have congenital or acquiredhypogonadotropic hypogonadism with concomitant human chorionicgonadotropin (hCG) therapy.

In an embodiment the medicament comprises Reslizumab. Reslizumab ismarketed as Cinqair®. Reslizumab is an interleukin-5 antagonistmonoclonal antibody (IgG4 kappa) for use in add-on maintenance treatmentof patients with severe asthma aged 18 years and older, and with aneosinophilic phenotype (1). Reslizumab is an FDA approved antibody. Themarket authorisation holder is Teva Respiratory LLC.

In an embodiment the medicament comprises an anti-CGRP antibody, whichmay be referred to as Fremanusumab. The anti-CGRP antibody may beproduced by expression vectors having deposit numbers of ATCC PTA-6867and ATCC PTA-6866 as disclosed in application WO2007054809.

As used herein, the term “contiguous” may refer to a close proximity,including within 1-2 mm or 1-4 mm or other amount, without actuallytouching.

As used herein, the term “channel” may include a cut-out or groove likeportion of the packaging that provides a containing function in respectof the injection device. The channel may include a U-section, V-sectionor other suitably profiled section. The channel may extend around aportion of an accommodated injection device to cover the portion of saiddevice. The channel may be arranged to abut and/or to be contiguous anaccommodated injection device. The channel may substantially conform tothe shape of the injection device. The channel may be formed withlongitudinal walls adjoined by a base wall. A base wall of the channelcan be distinguished from a longitudinal/lateral wall by a portion ofthe channel that comprises a directional vector of extension with alongitudinal/lateral component greater than a depth component.

As used herein, the term “recess” may include a cut-out or groove likeportion of the packaging. In embodiments a handling recess may bearranged to provide user access, via one or more digits of a hand of auser, to a depth position of the channel to enable gripping of aninjection device accommodated in the channel. The handling recess may bearranged adjacent to and extend orthogonal the channel (and therefore anaccommodated injection device). In embodiments a positioning recess isarranged to receive a rib of the channel to locate the device in thechannel. The recess may include a U-section, V-section or other suitablyprofiled section. The recess can be formed with longitudinal/lateralwalls adjoined by an adjoining wall. An adjoining wall of the recess canherein be distinguished from a longitudinal/lateral wall by a portion ofthe recess that comprises a directional vector of extension with alateral/longitudinal component greater than a depth component.

As used herein, the term “longitudinal” refers to a direction aligned toa length of the channel, and thus a longitudinal axis of an accommodatedinjection device.

As used herein, the term “lateral” refers to a direction aligned to awidth of the channel, and thus a width of an accommodated injectiondevice. The lateral direction is orthogonal to the longitudinaldirection.

As used herein, the term “depth” refers to a direction aligned to adepth of the channel, and thus a depth of an accommodated injectiondevice. The depth direction refers to the depth of the packaging whenviewed from a packaging planform in a laterally and longitudinallyextending plane.

In the accompanying figures the longitudinal, lateral and depthdirections are designated by respective ‘L’, ‘W’ and ‘D’.

The term “above” with reference to the packaging refers to a positionlocated above the planform when viewed in the depth direction. The term“below” with reference to the packaging refers to a position locatedbelow a base of the packaging when viewed in the opposed depthdirection. The term “top” refers to a portion of the packaging thatforms part of the planform when viewed from above. The term “bottom”refers to a portion of the packaging that abuts a support surface, suchas a table, when the injection device is to be extracted from thechannel.

The terms “proximal” and “distal” when used in reference to theinjection device refer to a longitudinal position in respect of adelivery end of the device. When used in reference to the packaging theyrefer to a longitudinal position associated with the delivery end of aninjection device accommodated in the channel.

The term “concave” when used in reference to the formation of thepackaging may refer to a surface that is arranged to extend inwardly,including curved (e.g. a C-shape) and/or linear (e.g. a U-shape). Theterm “convex” when used in reference to the formation of the packagingmay refer to a surface that is arranged to extend inwardly, includingcurved (e.g. a C-shape) and/or linear (e.g. a U-shape).

The present disclosure provides packaging suitable for a medicalinjection device, which includes suitability in that the packaging isdimensioned to accommodate a typical injection device, and thus includessuitability for injection training devices with dimensions correspondingto those of the associated injection device. Suitability for a medicalinjection device also includes that the packaging may be certified tovarious standards for leakage, ageing and porosity. Said standards mayinclude the US Food and Drugs Association (FDA) Consensus Standards, asdefined by the Institute of Packaging Professionals, Medical devicePackaging Technical Committee, including D3078:1994; F1608:2000; andF1980:2002.

Referring to FIG. 1 and FIG. 2 , embodiment packaging 2 for an injectiondevice 4 comprises a channel 6 that extends in the longitudinaldirection L to accommodate the injection device. The channel 6 is formedby a first longitudinal wall 8 and a second longitudinal wall 10, whichare interposed by an adjoining base wall 12.

A handling recess 14 enables handling of the injection device 4accommodated in the channel 6. The handling recess 14 extends in thelateral direction and is formed through the first longitudinal wall 8.

A positioning rib 22 is arranged to protrude from the base wall 12 intothe channel 6. The positioning rib 22 is adapted to position theinjection device 4 in the channel 6 via insertion into a complementarypositioning recess 24 of the injection device 4.

The positioning rib 22 is arranged offset laterally from the handlingrecess 14. In respect of the positioning rib arranged offset laterallyfrom the handling recess 14, meant that the rib occupies a distinctlateral position from that of the handling recess, e.g. there is aportion of the base wall 12 of the channel 6 arranged therebetween.

The positioning rib 22 is arranged extending in a longitudinal field 15defined by the handling recess 14. By arranged within (or extending in)a longitudinal field it is meant that part or all of the positioning rib22 occupies the same longitudinal position as the handling recess 14.The handling recess 14 thus defines a longitudinal field/locus that isbounded/marked off by the longitudinal extremities of the handlingrecess.

The injection device 4 and channel 6 are complementary in shape suchthat the injection device 4 can be suitably accommodated in the channel6.

The injection device 4 includes a body 29, which extends longitudinallybetween a distal end 30 and proximal end 32, the proximal end 32 isadapted for delivery of the medicament. Said adaptation may comprises asubcutaneous delivery member (not shown) or a connector (an exampleincludes a Luer connector) for receiving said member or other suitableconfiguration. Example of subcutaneous delivery members include ahypodermic needle. A removable end cap 35 may be arranged at theproximal end 32 to protect the subcutaneous delivery member.

The injection device 4 includes the positioning recess 24 arranged inthe body 29 to extend in the longitudinal direction between the distalend 30 and proximal end 32. The positioning recess 24 includes a firstrecess end 34 and a second recess end 36. The positioning recess 24 iscomplementary in shape to the positioning rib 22. The first recess end34 and second recess end 36 are longitudinally disposed to receive inabutment and/or contiguously a corresponding first rib end 26 and secondrib end 28 of the positioning rib 22.

The positioning recess 24 includes first longitudinal wall 25, a secondlongitudinal wall 27 adjoined by a base wall 29. The first recess end 34and a second recess end 36 comprise a respective distal lateral 31 and aproximal lateral wall 33 that adjoins the walls 25, 27 and 29. The walls25, 27, 29, 31 that form the sides and ends of the positioning rib aregenerally planar, although alternative configurations are included inthe disclosure, including curved. The configuration of said walls of thepositioning recess generally corresponds to those of the positioning rib22 as will be discussed.

The positioning recess 24 includes a delivery window for visual feedbackof medicament delivery. The delivery window is formed as at least partof a base wall 29 of the positioning recess 24.

The injection device 4 includes a further positioning recess 38corresponding to the positioning recess 24 (the disclosure also includesembodiments with a single such recess). The further positioning recess38 is arranged on the body 29 longitudinally aligned and opposed to thepositioning recess 24. With one of the positioning recesses 24, 38receiving the positioning rib 22 of the packaging 2, the delivery windowof the other positioning recess 24, 38 can be observed when viewing fromthe planform of the packaging 2. A user may be notified of the operativestate of the injection device before/whilst removing the injectivedevice 4 from the packaging 2.

The injection device 4 includes a label 52 arranged on the body 29. Thelabel 52 may include instructions for operation of the injection device(IFU) and/or a dosage regimen selected for the medicament. The label 52is arranged relative to the or each positioning recess 24, 38 to bevisible when viewing the planform of the packaging 2 accommodating thedevice 4. For example, the label 52 is orientated equidistantly (orapproximately equidistantly, which may include an offset of ±10 or 20%)about a longitudinal axis 11 that extends through a positioning recess24, 38 or is otherwise suitably arranged. A user may thus be notified ofthe label before/whilst removing the injection device 4 from thepackaging 2. The label 52 is arranged at a different longitudinalposition to the positioning recess 24, 38. Since the positioning recessis aligned to the handling recess 14, it is ensured that a user does notobscure the label when gripping an accommodated device 4. The disclosureincludes embodiments with alternatively arranged label. A label mayrefer to a portion of material adhered to the body, or otherwiseattached thereto. A label may be formed in the body by printing,embossing, moulding, stamping or otherwise.

The handling recess 14 is arranged to ensure the proximal end 32 of theinjection device 4 is not gripped during extraction. Gripping of theproximal end 32 may result in one or more of: damage to the user; damageto the subcutaneous delivery member; dislodging of the end cap. In otherembodiments the handing recess 14 can be arranged to control gripping atany part of the injection device 4.

In embodiments the injection device 4 may be replaced with acorresponding injection device training device, which can include thesame components, geometric shape of the injection device and operabilitybut without medicament delivery capability. Typically the device isdimensioned with a longitudinal length of 10-30 cm and a cross-sectionalarea of 0.8-20 cm².

Referring to FIG. 3 embodiment arrangements of the positioning rib withrespect to the longitudinal field 15 include: the positioning rib 22 awith both ends aligned to the periphery of the longitudinal field 15;the positioning rib 22 b, 22 c with one end aligned to the periphery ofthe longitudinal field 15 and the other arranged outside of thelongitudinal field 15; the positioning rib 22 d with both ends arrangedoutside of the longitudinal field 15 and the rib extending in thelongitudinal field 15; the positioning rib 22 e, 22 f with both endsarranged outside of the longitudinal field 15 and the rib extendingoutside the longitudinal field 15; the positioning rib 22 g with bothends aligned to the periphery of the longitudinal field 15 and formed ofseveral protrusions; the positioning rib 22 h with neither end alignedto the periphery of the longitudinal field 15 and arranged within of thelongitudinal field 15. It will be understood that in such embodimentsthe positioning recess 26 is correspondingly arranged to locate the endsof the injection device 4 in the desired position in the channel 6.

With further reference to FIGS. 1 and 2 , the handling recess 14 isformed by a first lateral wall 16 and a second lateral wall 18, whichare interposed by an adjoining wall 20. The positioning rib 22 comprisesa first rib end 26 a and second rib end 28 and extends laterallytherebetween.

The first rib 26 end and second rib end 28 are aligned in thelongitudinal direction to the respective first lateral wall 16 andsecond lateral 18 wall of the handling recess 14. The positioning rib 22is therefore arranged entirely within the longitudinal field 15 of thehandling recess 14.

In respect of the first rib end 26 and second rib end 28 arrangedaligned longitudinally to the respective first lateral wall 16 andsecond lateral wall 18 of the handling recess 14, it is to be understoodthat a portion that forms an end lateral wall of the rib, which mayinclude a portion interconnecting the rib and base wall 12 of thechannel 6 or a portion interconnecting the end lateral wall of the ribwith a top adjoining wall of the rib (e.g. a round or chamfered or otherlike connection), overlaps a longitudinal position of part of theassociated lateral wall 16, 18.

In embodiments with an inclined first lateral wall 16 and/or an inclinedsecond lateral wall 18 (an example of which is shown in the embodimentof FIGS. 3-6 ) it is to be understood that the associated rib end can belongitudinally aligned to a longitudinal field 15 that spans thelongitudinal distance of the incline.

In variant embodiments, one or both of the first rib end 26 and secondrib end 28 are arranged outside of the longitudinal field 15 defined bythe handling recess 14. The positioning rib 22 thus has a greaterlongitudinal length than the longitudinal field 15 of the handlingrecess 14. In an embodiment, one or both of the first rib end 26 andsecond rib end 28 are arranged within the longitudinal field 15 of thehandling recess 14 and aligned to the adjoining wall 20 of the handlingrecess 14. The positioning rib 22 thus has a lesser longitudinal lengththan the longitudinal field 15 of the handling recess 14.

Referring to FIGS. 4-13 an example comprises features within the scopeof the preceding embodiments. The channel 6 includes the firstlongitudinal wall 8 and second longitudinal wall 10 arranged to extendalong inclined planes that intersect at an apex arranged depth D below abase of the packaging 2. The inclined planes are truncated by theadjoining base wall 12. The inclination of the planes relative to thedepth direction is 2-5°, however in other embodiments it may be 2-20° orother suitable amount. The adjoining base wall 12 is generally alignedin a plane extending in the longitudinal L and lateral W directions.Thus the channel 6 has a generally truncated V-shaped cross-section. Thelongitudinal walls 8, 10 and base wall 12 may adjoin along a straightedge or with a round, which may have a radius of 0.5-4 mm, or otherprofile including a chamfer.

In variant embodiments, which are not illustrated, the channel may haveother suitable sections. One example is a U-shaped section, whereinfirst longitudinal wall and second longitudinal wall arranged aligned toeach other and to the depth direction. Another example is a sectionwhich is profiled to conform to that of the injection device, e.g. apartially circular or curved cross section to conform to that of theembodiment injection device shown in FIG. 1 . In such an example thesection may follow that of the injection device such that it is eitherin abutment or continuous thereto. In other embodiments theaforedescribed channel sections may be combined.

Referring to FIG. 6 , the first longitudinal wall 8 includes a firstface 40, which faces the channel 6, and a second face 42, which facesaway from the channel 6. The second longitudinal wall 10 includes afirst face 44, which faces the channel 6, and a second face 46, whichfaces away from the channel 6.

A peripheral longitudinal wall 50 is arranged adjacent the firstlongitudinal wall 8. The peripheral longitudinal wall 50 forms aperipheral wall of the packaging 2. The peripheral longitudinal wall 50,comprises a first face 54, which faces away from channel 6, and a secondface 56, which faces the channel 6. The peripheral longitudinal wall 50is inclined to the first longitudinal wall 8, such that both wallsextend along inclined planes that intersect at an apex arranged abovethe packaging 2. The inclination of the planes relative to the depthdirection may be 1-5° or other amount. The inclined planes are truncatedby a top adjoining wall 64, which adjoins the peripheral longitudinalwall 50 first longitudinal wall 8. The inclination of the walls 8, 50may aid in stacking, in the depth direction, of like packaging.

An additional first longitudinal wall 58 is arranged adjacent the secondlongitudinal wall 10. The first longitudinal wall 58 forms an adjacentchannel 48 for accommodating a further injection device. In theembodiment three such channels are provided. The first longitudinal wall58, comprises a first face 60, which faces the channel 48, and a secondface 62, which faces away from the channel 48. The first longitudinalwall 58 is inclined to the second longitudinal wall 10, such that bothwalls extend along inclined planes that intersect at an apex arrangedabove the packaging 2. The inclination of the planes relative to thedepth direction may be 1-5° or other amount. The inclined planes aretruncated by a top adjoining wall 64, which adjoins the firstlongitudinal wall 58 and second longitudinal wall 10. The inclination ofthe walls 10, 58 may aid in stacking, in the depth direction, of likepackaging.

The adjacent channel 48 and further channel and associated forming wallsmay comprise a similar configuration to that of the channel 8, thus forbrevity they are not described herein. For convenience the peripherallongitudinal wall 50 and first longitudinal wall 58 may be referred togenerally as a further longitudinal wall when referring to the channel8.

In variant embodiments, which are not illustrated, there may be anysuitable number of channels for accommodation of injection devices,including 1-6. The peripheral wall and/or first longitudinal walladjacent the second longitudinal wall may be omitted, e.g. in anembodiment with only a single channel. In embodiments when present theymay be alternatively arranged, including aligned in the depth direction.

Referring to FIG. 5 , the first lateral wall 16 and the second lateralwall 18 of the handling recess 14 extend along inclined planes 19 thatintersect at an apex 21. The apex 21 is arranged below the packaging 2,e.g. a base thereof. The extension of the lateral walls 16, 18 istruncated by the adjoining wall 20. The inclination of the planes 19relative to the depth direction may be 30-55° or other amount. Theinclination of the lateral walls 16, 18 provides a wider mouth at a topof the handling recess 14, which may aid a user when inserting a digitinto said recess, e.g. by providing a shape that corresponds to thedigit and/or by guiding the digit to a central location of the handlingrecess from which it is most appropriate to grip the injection device 4.The inclination of the lateral walls 16, 18 (compared to lateral wallsthat extend from the same mouth separation and that are aligned in thedepth direction) may provide a rigid region proximal the adjoining wall20.

The lateral walls 16, 18 adjoin the adjoining wall 20 with a round,which may have a radius of 5-20 cm or other amount. The round mayprovide a more rigid region proximal the adjoining wall 20 and mayconform to a shape of a digit of a user.

The base wall 12 of the channel 6 has a greater depth than the adjoiningwall 20 of the handling recess 14. The base wall thus forms areinforcing rib that extends in the longitudinal direction and protrudesin the opposed depth direction adjacent the channel 6. Such anarrangement may provide a rigid region proximal the adjoining wall 20,when compared to an embodiment (which is also included in thedisclosure) wherein the base wall 12 of the channel 6 has the same depthas the adjoining wall 20 of the handling recess 14.

In variant embodiments, which are not illustrated, the first and secondlateral walls 16, 18 may be alternatively arranged, including aligned inthe depth direction. The adjoining wall 20 may be alternativelyarranged, including arranged at the same depth as and/or inclined to thebase wall 12. One or more of the adjoining wall 20, first and secondlateral walls 16, 18 may be alternatively profiled, including curved orstepped or straight edged.

Referring to FIG. 3 , in an embodiment the adjoining wall 20 may includea reinforcing rib 23 protruding into the handling recess 14. Thereinforcing rib 23 may provide additional stiffening of the handlingrecess 14. The reinforcing rib 23 extends longitudinally from the firstand second lateral walls 16, 18. The reinforcing rib 23 is laterallyoffset from the first longitudinal wall 8. The offset may enable a userto more conveniently insert their digits into the handling recess 14 togrip the injection device 4. The reinforcing rib 23 has a lateral widthof less than between the first longitudinal wall 8 and secondlongitudinal wall 50. In variant embodiments, which are not illustrated,the reinforcing rib may be alternatively arranged, including centrallyaligned and extending from only one of the first and second lateralwalls 16, 18.

Referring to FIG. 7 , the handling recess 14 is formed through thefurther longitudinal wall 50 (in addition to the previously discussedfirst longitudinal wall 8) the first and second lateral walls 16, 18 andadjoining wall 20 thus bridge said longitudinal walls. Such anarrangement may provide a handling recess 14 which has enhanced rigiditycompared to an arrangement without said bridging.

The packaging includes a second handling recess 82. The second handlingrecess 82 is formed through the first longitudinal wall 58 and secondlongitudinal wall 10. The second handling recess 82 is complementary tothe handling recess 14, and is thus comprises like components, which forbrevity are not described. The second handling recess 82 islongitudinally aligned to the handling recess 14. The second handlingrecess 82 and first handling recess 14 may each be used by opposeddigits of a user when gripping an injection device 4 accommodated in thechannel 6 as will be discussed. The disclosure also includes handlingrecesses that are not complementary, including differing geometry andlongitudinal alignment.

Referring to FIGS. 3 and 6 , the first longitudinal wall 58 and secondlongitudinal wall 10 comprise respective opposed indentations 66, 68adapted for gripping of the packaging 2. Said adaption comprises agripping wall 70 arranged with a local depth that extends in the globallateral W direction. The gripping walls 70 may be separated by 4-12 mmor other suitable distance. The gripping wall is dimensioned to fit adigit of a user, e.g. a length in the longitudinal direction L of 2-4 cman adjoining semi-circular section arranged distal the top adjoiningwall 64. Such an arrangement provides a narrowing portion, which may bemore convenient to grip then portions of the walls 10, 58 without theindentations, e.g. the narrowing portion enables a greater lateral forceto be applied by opposed digits. The indentations extend in the globaldepth direction from the top adjoining wall 64. Such an arrangement mayreduce air locking of stacked packaging since the indentation provides aconduit for pressure relief that extends from the top adjoining wall 64to a particular depth.

In a variant embodiment, which is not illustrated, the indentations mayhave other arrangements, including discrete from the adjoining wall 64and/or with an alternatively profiled gripping wall. In embodimentspackaging 2 comprising indentations 64, 66 that are formed without thepreviously described positioning rib 22 and/or handling recess 14.

The indentations 66, 68 may aid in separating like packaging 2 stackedin the depth direction. The stack may be suppled in an open toppedcontainer wherein only the planform of the packaging is user accessible.

Referring to FIG. 8 , the positioning rib 22 has a generally U-shapedcross-section. The lateral position of the rib is central in the channel6, although the disclosure also includes an eccentric lateralarrangement. The positioning rib 22 includes a first longitudinal wall72 and a second longitudinal wall 74 interposed by an adjoining top wall77. The first longitudinal wall 72 and the second longitudinal wall 74adjoin the base wall 12 of the channel 6.

The first longitudinal wall 72 and a second longitudinal wall 74 arealigned in the depth direction D. In a variant embodiment, which is notillustrated, the first longitudinal wall and the second longitudinalwall of the positioning rib extend along inclined planes (e.g. with a5-20° incline relative to the depth direction) that intersect at an apextruncated by the adjoining top wall. Such tapering of the positioningrib 22 may facilitate easier locating with the positioning recess 24 andsubsequent insertion. The first longitudinal wall 72 and a secondlongitudinal wall 74 are generally planar, although alternativeconfigurations are included in the disclosure, including curved.

A round adjoins the top wall 77 with the first longitudinal wall 72 andthe second longitudinal wall 74. The round may have a radius of 1-3 mmor other suitable amount. Compared to an embodiment (which is alsoincluded in the disclosure) with straight edged adjoining walls,embodiments with a round may reduce air locking when the positioning rib22 is accommodated in the positioning recess 24 of the injection device4. The round may aid in guiding the rib into the recess during insertionof the injection device 4 into the channel 6. In embodiments the edge isalternatively profiled, including chamfered.

A round adjoins the base wall 12 of the channel 6 and the positioningrib 22. The round may have a radius of 1-3 mm or other suitable amount.The round may reduce air locking when the positioning rib 22 isaccommodated in the positioning recess 24 of the injection device 4. Theround may increase flexural rigidity of the rib 22 compared to anembodiment (which is also included in the disclosure) with straightedged adjoining walls. In embodiments the edge is alternativelyprofiled, including chamfered.

Referring to FIG. 4 , the positioning rib 22 includes, arranged at therespective first rib end 26 and second rib end 28 a proximal lateralwall 76 and a distal lateral wall 79. The proximal lateral wall 76 and adistal lateral wall 79 may be similarly configured as for the adjacentfirst longitudinal wall 72 and a second longitudinal wall 74 in terms oforientation in the depth direction and connection with adjoining edgesand optional taper. The proximal lateral wall 76 and distal lateral wall79 are generally planar, although alternative configurations areincluded in the disclosure, including curved, including by a full round.

Referring to FIG. 8 , the adjoining top wall 77 of the positioning rib22 is generally planar in the lateral direction W. The base wall 29 ofthe positioning recess 24 is convex in the lateral direction W. Thepositioning recess 24 and positioning rib 22 are thus adapted to form alaterally extending concave shaped gap 9 between the top wall 77 of thepositioning rib 22 and the base wall 29 of the positioning recess 24when in an arrangement with the positioning recess 24 accommodating thepositioning rib 22.

Referring to FIG. 9 , the adjoining top wall 77 of the positioning rib22 is convex in the lateral direction W. The base wall 29 of thepositioning recess 24 is convex in the lateral direction W. Thepositioning recess 24 and positioning rib 22 are thus adapted to form alaterally extending convex shaped gap 9 between the top wall 77 of thepositioning rib 22 and the base wall 29 of the positioning recess 24when in an arrangement with the positioning recess 24 accommodating thepositioning rib 22.

Referring to FIG. 10 , the adjoining top wall 77 of the positioning rib22 is generally planar in the lateral direction W. The base wall 29 ofthe positioning recess 24 is concave in the lateral direction W. Thepositioning recess 24 and positioning rib 22 are thus adapted to form alaterally extending convex shaped gap 9 between the top wall 77 of thepositioning rib 22 and the base wall 29 of the positioning recess 24when in an arrangement with the positioning recess 24 accommodating thepositioning rib 22.

Referring to FIG. 11 , the adjoining top wall 77 of the positioning rib22 is concave in the longitudinal direction L. The base wall 29 of thepositioning recess 24 is generally planar in the lateral direction W.The positioning recess 24 and positioning rib 22 are thus adapted toform a longitudinally extending convex shaped gap 9 between the top wall77 of the positioning rib 22 and the base wall 29 of the positioningrecess 24 when in an arrangement with the positioning recess 24accommodating the positioning rib 22.

The embodiment of FIG. 11 may be combined with any of those associatedwith FIGS. 8-10 . In an embodiment, which is not illustrated, thelongitudinally extending convex shape gap may be alternatively formed,including by a longitudinally concave base wall of the positioningrecess and a generally planar adjoining top wall of the positioning ribor combinations thereof.

In the preceding embodiments, the lateral concavity may be formed withradii of 2-10 mm, or be alternatively curved, including with a maximumdepth from the longitudinal walls 72, 74 of 0.25-2 mm or 0.5-1 mm or5-20% of the width of the rib. In the preceding embodiments, thelongitudinal concavity may be formed with radii of 0.1-0.5 m, or bealternatively curved, including with a maximum depth from the lateralwalls 76, 79 of 0.5-3 mm or 0.5-2 mm or 5-20% of the length of the rib.The lateral/longitudinal convexity can be arranged with the equivalentdimensions as for the concavity, which for brevity is not repeated. Ingeneral the geometric extent of the concavity/convexity is selected toprevent the rib/recess flexing into each other.

As used herein the term “concave shaped gap” or “convex shaped gap” mayrefer to a shape of a gap between and formed one or both opposedsurfaces of the positioning rib and position rib. The concave/convexshaped gap may extend in the lateral and/or longitudinal directions.

A convex shaped gap 9 may prevent/reduce a portion of the portioning rib22 flexing into the base wall 29 of the positioning recess 24 of theinjection device 4, for instance when in use the top wall 77 of thepositioning rib is subject to a compression load. Flexing of the topwall 77 into the base wall 29 may damage the injection device,particularly if the base wall 29 comprises the aforedescribed deliverywindow, e.g. by marking or otherwise obscuring the peripheral surface.

In the illustrated embodiments the first longitudinal wall 25 and secondlongitudinal wall 27 of the positioning recess 24 abut the correspondingfirst longitudinal wall 72 and second longitudinal wall 74 of thepositioning rib 22. It will be understood that portions of one or moreof the side, end, top and base walls of the positioning rib/recess maybe arranged contiguous and/or in abutment to provide the intendedpositioning of the injection device 4 in the packaging 2.

Referring to FIGS. 4 and 7 , the channel 6 includes closing portionscomprising a laterally extending proximal end wall 78 and a laterallyextending distal end wall 80. The packaging 2 and injection device 4including the respective positioning rib 22 and positioning recess 24arranged to locate the injection device 4 in the channel 6 with thedistal end 30 and proximal end 32 thereof apart from the respectivedistal end wall 80 proximal end wall 78. Separating the ends of theinjection device from the ends of the channel may reduce risk of damageof the injection device, e.g. a delicate end cap 35 of the proximal end32 of the injection device 4 is maintained out of abutment with thepackaging 2, wherein abutment may effect transfer of load, in case of animpact, to dislodge the endcap. Dislodging of the end cap 35 may causedamage to the subcutaneous delivery member and/or could make theinjection device dangerous to handle.

The separation between the proximal end 32 of the injection device 4 andproximal end wall 78 of the packaging 2 may be less than thelongitudinal displacement to separate the end cap 35 from the proximalend 32. Separation of the end cap 35 within the packaging 2 may therebybe prevented.

During insertion of the injection device 4 into the packaging 2, theproximal end wall 78 and distal end wall 80 may provide a coarsealignment for the injection device 4 in the channel 6, with finealignment being subsequently provided by the engagement of thepositioning rib 22 and positioning recess 24. In an embodiment theaforedescribed tapering of the proximal end wall 78 and distal end wall80 of the positioning rib 22 may transition during said insertion (viaengagement with the positioning recess 24) the injection device 4 fromabutment from one of the proximal or distal end wall 78, 80 to apositioning rib 22 controlled longitudinal location.

In variant embodiments, which are not illustrated, one or both of theproximal end wall 78 and distal end wall 80 may be omitted.

The positioning recess 24 is longitudinally offset with respect to thelongitudinal axis of the injection device 4. In a like manner, thepositioning rib 22 is longitudinally with respect to the longitudinalaxis of the channel 6 of the packaging 2. With such a configuration(compared to the rib and recess being arranged longitudinally centred)the longitudinal orientation of the injection device 4 in the packagingcan be controlled, e.g. with the proximal end 32 of the injection device4 arranged at the intended proximal end of the packaging 2. Thearrangement may be further controlled by the inclusion of the proximalend wall 78 and the distal end wall 80 of the channel 2, which can bedisposed to block accommodation of the positioning rib 22 in thepositioning recess 24 when the proximal end 32 of the injection device 4is arranged proximal the distal end of the packaging (or the converse).It is to be understood that the disclosure also includes centrallyaligned positioning ribs and/or recesses.

The positioning rib 22 and positioning recess 24 can be transitionedbetween a separated position and an accommodated position (as shown inFIGS. 9 and 10 ), in which the positioning rib 22 is accommodated in thepositioning recess 24 to position the injection device 4 in the channel6.

In the accommodated position the positioning recess 24 stiffens thepackaging 2. Since the geometry of the positioning recess 24 correspondsto the positioning rib 22, the positioning recess 24 can restraindisplacement of portions of the accommodated positioning rib 22, saidportion can include one or more of the rib: proximal lateral wall 76;distal lateral wall 79; first longitudinal wall 72; second longitudinalwall 74; adjoining top wall 77 (generally in embodiments which do notcomprise a adjoining top wall 77).

In the accommodated position the positioning rib 22 and positioningrecess 24 may be adapted with various fits. In an embodiment said fitincludes a locating fit that does not require an insertion and/orextraction force to transition to/from the accommodated position. Such afit can be achieved by arranging the positioning rib 22 and positioningrecess 24 to have entirely corresponding dimensions and/or thepositioning recess 24 to have corresponding dimensions that are greaterthan those of the positioning rib 22 (or the positioning rib 22 to havecorresponding dimensions that are less than those of the positioning rib24).

In an embodiment said fit includes a force-fit that implements aninsertion and/or extraction force to transition to/from the accommodatedposition. Such a fit can be achieved by arranging the positioning rib 22to be in an at least partially compressed state when arranged in theaccommodated position. The compressed state can be achieved bydimensioning the positioning recess 24 to be smaller than thepositioning rib 22, which may include forming part or all of thelongitudinal length and/or lateral width of the positioning recess 24 tobe less (e.g. by 1-5%) than the corresponding dimension of thepositioning rib 22. The compressed state can be achieved by forming thepositioning rib 22 to be displaceable in the accommodated position,including via elastic and/or plastic material deformation.

In like embodiments the force-fit is achieved by arranging thepositioning recess 24 to be in an at least partially expanded state whenarranged in the accommodated position, which in further embodiments maybe combined with the positioning rib 22 in the compressed state.

In embodiments a force-fit is achieved by arranging the positioning rib22 and positioning recess 24 to have entirely corresponding dimensionswhereby a material friction coefficient provides theextraction/insertion force.

In an embodiment the force-fit includes an extraction force, totransition from the accommodated position to the separated position,less than a weight of the packaging 2. In an embodiment the mass of thepackaging may be 100 grams, wherein the extraction force is less than 1Newton. It will be understood that the force may vary depending on theconfiguration (and thus the mass) of the packaging 2, e.g. it can beless than 0.5, 1.5 or 2 Newton. With such an arrangement the packaging 2may remain in abutment with an abutment surface (e.g. a table) when thedevice 4 is extracted from the channel 6, and thus the positioning rib22 retracted from the positioning recess 24.

In embodiments: the positioning rib 22 has a nominal longitudinal lengthof up to 1.5 or 1 or 0.5% less than that of that of the positioningrecess 24; the positioning rib 22 has a nominal lateral width of up to 4or 6 or 8% less than that of that of the positioning recess 24.

In embodiments: the positioning rib 22 has a nominal longitudinal lengthof 38.6 mm and a nominal lateral width of 5.2 mm; and the positioningrecess 24 has a nominal longitudinal length of 38.8 mm and a nominallateral width of 5.4 mm. In embodiments each of the described dimensionsmay be may be ±1% or 5% or 10%. The total distance between thepositioning rib 22 and positioning recess 24 in the lateral andlongitudinal direction may be 0.2 mm±1% or 5% or 10%.

In embodiments the positioning rib 22 is operatively arranged forstiffening of the handling recess 14, e.g. the positioning rib 22increases the resistance of the packaging to bending moment appliedabout a laterally extending axis. The handling recess 14 may bestiffened in terms of a flexural rigidity extending longitudinally alongsaid recess. The positioning rib 22 thus compensates for the loss ofstiffness due to the formation of the handling recess 14 through theassociated walls. Suitable arrangements of the positioning rib 22 mayinclude the geometric configuration of the rib (e.g. one or more of thelength, depth, width) specifically selected for stiffening. Saidarraignment may include the positioning of the rib (e.g. aligned to thehandling recess 14).

In embodiments the positioning rib 22 has a depth ‘d’ of about 25% or20-30% of a depth of the recess 14 (i.e. the nominal depth of theadjoining wall 20 from the top adjoining wall 64 of the handling recess14). In embodiments the positioning rib 22 has a longitudinal length ‘l’about 24% or 20-30% or 15-35% of a longitudinal length of the channel 6.In embodiments the positioning rib 22 has a lateral width ‘w’ of about3% or 2-4% of a longitudinal length of the channel 6. In embodiments thepositioning rib 22 has a lateral width of about 20% or 15-25% of alateral width of the channel 6. In embodiments j is about 8% or 6-10% or4-15% or 2-20% of the product of w and d³.

Referring to FIGS. 4, 7 and 12 the channel 6 includes laterallyextending abutment ribs 84, 85. The abutment ribs 84, 85 are arranged toabut the injection device 4 accommodated in the channel 6. The abutmentribs 84, 85 include curved protrusions that protrude into the channel 6.The abutment ribs 84, 85 may stiffen sections of the channel. Theabutment ribs 84 are arranged within the longitudinal field 15 of thelateral walls 16, 18 of the handling recess 14. The abutment rib 85 isarranged at the distal end of the channel 6. The abutment ribs 84, 85are formed of a single protrusion.

The abutment ribs 84, 85 may prevent/reduce lateral movement of theinjection device 4 accommodated in the channel 6. The abutment ribs 84,85 may control portions of the body 29 of the device 4 abutted by thepackaging. The portion abutted may receive wear due to friction, thusthe abutment ribs 84, 85 may localise such wear. In an example, the wearmay be directed away from the label 52 so as to avoid obscuringinstructions thereof.

In variant embodiments, which are not illustrated, the abutment ribs maybe alternatively arranged, e.g. the abutment ribs may be protrude withother suitable shapes including V-shaped or Square-shaped. The abutmentribs may be formed of multiple adjacent protrusions. The abutment ribsmay be alternatively located, including at the proximal end of thechannel.

Referring to FIGS. 12 and 13 , the channel 6 includes longitudinallyextending cut-outs 86 arranged adjacent each longitudinal wall 72, 74 ofthe positioning rib 22. The cut-outs 86 project as cavities from thebase 12 of the channel in the depth direction D, hence in the opposeddirection to the positioning rib 22. The cut-outs 86 may enhancestiffness proximal the handling recess 14. The cut-outs 86 mayfacilitate more convenient gripping of an injection device 4accommodated in the channel 6 by enabling a user to partially inserttheir digits into the cut-outs when gripping the device 4.

Referring to FIG. 14 , the cut-outs 86 may protrude to abut the body 29of an injection device 4 accommodated in adjacent like packaging 3,which is stacked in the depth direction beneath the packaging 2. Thecut-outs 86 may restrain the abutted injection device 4.

Referring to FIGS. 14-17 , the packaging may be adapted to providevarious stacking configurations. Referring to FIG. 17 , the packaging 2is adapted to enable insertion into corresponding adjacent packaging 3.The insertion is to a first depth with the packaging 2, 3 bothcorrespondingly arranged in a first position. The first depth comprisesa substantial portion (e.g. at least 60-90%) of the depth of thepackaging such that packaging without an injection device accommodatedtherein can be conveniently stacked and stowed.

The adaptation may comprise a general correspondence of adjacentportions of the packaging 2, 3 including by tapering and rounding asdiscussed previously. Referring to FIG. 17 , the adaptation includesgrooves 88 arranged through an exterior face of a distal 90 and proximal92 peripheral lateral wall. Adjoining walls 94 adjoin the proximalperipheral lateral wall 92 and proximal end wall 78 of the channel 6,and the distal peripheral lateral wall 90 and distal end wall 80 of thechannel 6. The grooves 88 form corresponding protrusions 96 on opposedinterior faces of the peripheral lateral walls 90, 92. A protrusion 96of the packaging 2 is insertable into the groove 88 of packaging 3 forsaid stacking.

The grooves 88 extend in the depth direction to proximal a base of theperipheral walls 90, 92. The grooves have a generally curved crosssection, which may aid insertion of a corresponding protrusion.

Referring to FIGS. 15 and 16 , the packaging 2 is adapted to enableinsertion into corresponding adjacent packaging 3 to a second depth,which is less that the first depth, with the packaging 2, 3 arranged ina second position. In the second position the packaging 3 is rotatedabout the depth axis by 180° relative the packaging 2. In this positiona base 98 of the groove 88 of packaging 2 abuts the adjoining walls 94of packaging 3 to provide a stable abutment. The abutment may preventexcessive contact between an injection device 4 arranged in thepackaging 3 and the stacked packaging 2.

The abutment of the base 98 of the groove 88 of packaging 2 with theadjoining wall 94 of packaging 3 with the packaging 2, 3 arranged in thesecond position and the insertion of the protrusion 96 of packaging 2 into groove 88 of packaging 3 with the packaging 2, 3 arranged in thefirst position can be achieved by eccentrically arranging the grooves 88with respect to width. In the illustrated embodiment the eccentricarrangement comprises the groove 88 arranged proximal an end channel 6,rather than at the centre along the peripheral wall.

In embodiments, which are not illustrated, the grooves may bealternatively and/or additionally arranged, e.g. including though theperipheral longitudinal wall 50 or the channel 6. Reference to groovescan include formation on the interior or exterior face of a peripheralwall, or other wall. The grooves may be alternatively shaped, e.g.including a linear rather that curved cross section.

In variant embodiments, the positioning rib 22 may be formed of morethan one protrusion. An example includes a separate first protrusion andsecond protrusion arranged at the respective first rib end 26 and at thesecond rib end 28. Reference to a positioning rib herein may thereforerefer to a rib formed of one or a plurality of separated protrusions.

The packaging may be formed by thermoforming, vacuum forming, casting orother forming process known to the skilled person. Typically the singleplastic sheet in planar form is thermoformed to the desired profile viaa mould and other associated equipment known to the skilled person.Suitable materials for the plastic sheet include polystyrene. Suitablegauges for the plastic sheet prior to forming include 0.6 mm.

An embodiment method of stowing embodiment injection device 4 (or a likeconfigured injection device training device) in packaging 2 as disclosedherein may include arranging said the injection device 4 in an alignedposition with the first recess end 34 and the second end 36 of thepositioning recess 24 and/or 38 thereof longitudinally aligned with therespective first lateral wall 16 and the second lateral wall 18 handlingrecess 14. The user may displace the injection device 4 arranged in saidaligned position in the depth direction to insert it into the channel 6,which may include the positioning rib 22 and positioning recess 24 or 38arranged in the accommodated position.

Referring to an embodiment comprising: a second positioning recess 38arranged opposed and longitudinally aligned to the positioning recess24; and the associated first rib 26 ends and second rib ends 28 arrangedaligned in the longitudinal direction to the respective first lateralwall 16 and second lateral 18 wall of the handling recess 14. A user mayin the aligned position align the first rib 26 end and second rib end 28of the positioning recess 38, with said recess 38 arranged visible fromabove the packaging, with the first lateral wall 16 and second lateral18 wall of the recess 14, which therefore ensures longitudinal alignmentof the positioning rib 22 and positioning recess 24. Thus thearrangement of the positioning recess 38 and handling recess 14 may beused as a longitudinal guide during insertion.

In an embodiment method of extracting an injection device 4 (or a likeconfigured injection device training device) stowed in packaging 2 asdisclosed herein may include inserting a digit (not shown) of a userinto the handling recess 14. The insertion may include movement of saiddigit in the depth and/or lateral direction. The method may includegripping said device and extracting it from the channel 6. Extractingthe device 4 from the channel 6 may include transitioning thepositioning rib 22 and positioning recess 24 from the accommodatedposition to the separated position, including by displacement of theinjection device in the opposed depth direction. Gripping the device 4may include the application of a force in the lateral direction to thedevice by said digit arranged in the handling recess 14. In embodimentscomprising the handling recess 14 and a complementary second handlingrecess 82, gripping the device 4 may include the application of opposedlateral force by opposed digits, each arranged in one of the recesses14, 82.

From the described embodiments it will be understood that the packaging2 may enable convenient extraction of the injection device 4. Thehandling recess 14 conveniently enables a user to accesses the channel 6for gripping, by opposed digits, of the accommodated injection device 4.The injection device may by extracted without complex movements, such asrotation of the device and/or a hand of the user. It will thus beunderstood that the packaging is suited for use by users with a disorderthat effects dexterity. Thus the injection device 4 preferably includesa medicament for treatment or prevention of such an illness.

To close the channel 6, 48 of the packaging 2 and/or secure theinjection device 4 therein various arraignments (not shown) may beprovided, which may be referred to as a lid.

In an embodiment a tear away or break through lid may be provided asmedical blister type packaging. A lidding film may provide a peel-openfeature that can be peeled open using two-hands, including by aknuckle-roll-peel technique. The lidding film can be made from plastic,aluminium, medical grade papers, or other suitable material. A liddingfilm of a blister pack may be permeable to gas porous to allowsterilization but not permeable to microorganisms. A presently availableexample plastic material is Tyvek® by DuPoint™. The lidding film may bemade from a completely non-permeable or non-breathable film. Ininstances where a non-breathable film is used, sterilization can be viaan electron beam or similar.

In an embodiment, the lid may comprise a thick plastic sheet, which maycorrespond to that forming the channel 6, 48, thus providing a medicaltray or medical clamshell type packaging.

Embodiments are also provided according to the following clauses:

Clause 1. Packaging 2 for an injection device 4, the packaging mayinclude a channel 6 extending longitudinally to accommodate theinjection device, the channel including a longitudinal wall 8 adjoininga base wall 12; a handling recess 14 extending laterally and formedthrough the longitudinal wall 8, a positioning rib 22 extendinglongitudinally and protruding from the base wall into or away from thechannel for insertion into a positioning recess 24 of the injectiondevice, the positioning rib arranged offset laterally from the recess.The positioning rib may and extend in and/or outside of a longitudinalfield 15 defined by the handling recess.

Clause 2. The packaging of clause 1 or another embodiment disclosedherein, wherein the handling recess 14 including a first lateral wall 16and a second lateral wall 18 interposed by an adjoining wall 20. Thepositioning rib 22 may include a first rib end 26 a and second rib end28. The first rib end may be arranged: aligned longitudinally to thefirst lateral wall; arranged outside of the longitudinal field 15defined by the handling recess; arranged within of the longitudinalfield 15 defined by the handling recess. The second rib end may bearranged: aligned longitudinally to the second lateral wall; arrangedoutside of the longitudinal field 15 defined by the handling recess;arranged within of the longitudinal field 15 defined by the handlingrecess. Any combination of the preceding first and second rib endarrangements is included within the disclosure. The entire rib mayextend outside of or within the longitudinal field 15 defined by thehandling recess.

Clause 3. The packaging of either of clauses 1 or 2 or anotherembodiment disclosed herein, wherein the positioning rib 22 is formed asa single protrusion.

Clause 4. The packaging of any of clauses 2-3 or another embodimentdisclosed herein, wherein the first lateral wall 16 and the secondlateral wall 18 of the handling recess 14 extend along inclined planes19 that intersect at an apex 21 and are truncated by the by theadjoining wall 20.

Clause 5. The packaging of any preceding clause or another embodimentdisclosed herein, wherein the positioning rib 22 has a lateral width ‘w’a depth ‘d’ and the handling recess has a depth ‘j’, wherein j is 4-15%of the product of w and d³.

Clause 6. The packaging of any preceding clause or another embodimentdisclosed herein, wherein the positioning rib 22 includes a firstlongitudinal wall 72 and a second longitudinal wall 74 interposed by anadjoining top wall 77, the first longitudinal wall 72 and the secondlongitudinal wall 74 adjoining the base wall 12 of the channel 2.

Clause 7. The packaging of clause 6 or another embodiment disclosedherein, wherein a top wall 77 of the positioning rib 22 is concave inthe lateral direction.

Clause 8. The packaging of either clause 6 or clause 7 or anotherembodiment disclosed herein, wherein a round adjoins the adjoining topwall (77) with the first longitudinal wall (72) and the secondlongitudinal wall (74).

Clause 9. The packaging of any of clauses 6-8 or another embodimentdisclosed herein, wherein a round adjoins the base wall 12 of thechannel 6 and the positioning rib 22.

Clause 10. The packaging of any preceding clause or another embodimentdisclosed herein, wherein the positioning rib 22 is dimensioned with: alongitudinal length of 38.6 mm and a lateral width of 5.2 mm±5, or 10%or 20%.

Clause 11. The packaging of clause 2 or another embodiment disclosedherein, wherein the base wall 12 of the channel 6 is arranged with agreater depth than the adjoining wall 20 of the handling recess 14.

Clause 12. The packaging of any preceding clause or another embodimentdisclosed herein, wherein a further longitudinal wall 50 extendscontiguous the longitudinal wall 8 of the channel 12, the handlingrecess 14 formed through the further longitudinal wall 50.

Clause 13. The packaging of clause 12 or another embodiment disclosedherein, wherein the further longitudinal wall 50 and longitudinal wall8, comprise opposed indentations 66, 68 adapted for gripping of thepackaging, the indentations extending in a depth direction from a topadjoining wall 64, that interposes and adjoins the further longitudinalwall 50 and longitudinal wall 8.

Clause 14. The packaging of any preceding clause or another embodimentdisclosed herein, wherein a top wall 77 of the positioning rib 22 isconcave shaped and/or another shape suitable for preventing the top wallflexing into an adjacent surface of the positioning recess of theinjection device. The concave shape may extend in the lateral and/orlongitudinal direction. The concave shape may extend generally betweenouter walls (e.g. lateral or longitudinal wall that defines the rib).The concave shape may be generally curved and/or partially linear.

Clause 15. The packaging of any preceding clause or another embodimentdisclosed herein, wherein the base wall of the channel includeslongitudinally extending cut-outs 86 arranged on one or both sides ofthe positioning rib 22. The cut-outs may protrude in an opposeddirection to the positioning rib 22.

Clause 16. The packaging of any preceding clause or another embodimentdisclosed herein, wherein the channel 6 includes laterally extendingabutment ribs 84. The abutment ribs may be arranged proximal the ends ofthe positioning rib 22.

Clause 17. Packaging 2 for an injection device 4, the packaging mayinclude the packaging of any preceding clause or another embodimentdisclosed herein. The packaging may include: a channel 6 extendinglongitudinally to accommodate the injection device, the channelincluding a longitudinal wall 8 adjoining a base wall 12; a handlingrecess 14 extending laterally and formed through the longitudinal wall8, a positioning rib 22 extending longitudinally and protruding from thebase wall into the channel for insertion into a positioning recess 24 ofthe injection device, the positioning rib arranged offset laterally fromthe handling recess and arranged longitudinally in the channel tostiffen the handling recess, including a flexural rigiditylongitudinally along the handling recess.

Clause 18. Packaging 2 for an injection device 4. The packaging mayinclude the packaging of any preceding clause or another embodimentdisclosed herein. The packaging comprising: a channel 6 extendinglongitudinally to accommodate the injection device, the channelincluding a longitudinal wall 8 adjoining a base wall 12; a positioningrib 22 extending longitudinally and protruding from the base wall intothe channel for insertion into a positioning recess 24 of the injectiondevice, wherein a top wall 77 of the positioning rib 22 is concaveshaped.

Clause 19. A system comprising the packaging 2 of any preceding clauseor another embodiment disclosed herein, and an injection device 4, orinjection device training device, for accommodating in the channel 6 ofthe packaging, wherein said device comprises a positioning recess 24 toaccommodate the positioning rib 22.

Clause 20. The system of clause 19 or another embodiment disclosedherein, wherein, with the positioning recess 24 accommodating thepositioning rib 22, the positioning recess 24 of the device 4 and theadjoining top wall 77 of the positioning rib 22 are adapted to form aconvex shaped gap between the adjoining top wall of the positioning riband an opposed surface 29 of the positioning recess 24. The convexshaped gap may be in the lateral or longitudinal direction.

Clause 21. The system of either clause 19 or clause 20 or anotherembodiment disclosed herein, wherein the positioning recess 24 of thedevice 4 and positioning rib 22 of the packaging 2 are arranged tolocate the device in the channel 6 with: a distal end 30 of the devicearranged apart from a distal end wall 80 of the channel 6; and/or aproximal end 32 of the device arranged apart from a proximal end wall 78of the channel 6.

Clause 22. The system of any of clauses 19-20 or another embodimentdisclosed herein, wherein the positioning recess 24 of the device 4 arearranged to prevent accommodation of the injection device 4 in thechannel 6 with: a distal end 30 of the device arranged proximal theproximal end wall 78 of the channel 6; and/or a proximal end 32 of thedevice arranged proximal the distal end wall 80 of the channel 6.

Clause 23. The system of any of clauses 19-21 or another embodimentdisclosed herein, wherein the positioning recess 24 of the device 4 isarranged to be contiguous and/or in abutment with an accommodatedpositioning rib 24 of the packaging 2.

Clause 24. The system of any of clauses 19-23 or another embodimentdisclosed herein, wherein the device 4 comprises a further positioningrecess 38 arranged longitudinally aligned and opposed positioning recess24.

Clause 25. The system of any of clauses 19-24 or another embodimentdisclosed herein, wherein injection device 4 comprises a label 52, thepositioning rib 22, positioning recess 24 and label 52 arranged with thelabel visible from a planform of the packaging (e.g. when viewed in thedepth direction from above the packaging), with the positioning rib 22accommodated in the positioning recess 24 (e.g. with the injectiondevice accommodated in the channel).

Clause 26. The system of any of clauses 19-25 or another embodimentdisclosed herein, wherein injection device 4 comprises a label 52,wherein the label 52 is longitudinally offset from the positioning rib22.

Clause 27. The system of any of clauses 19-26 or another embodimentdisclosed herein, wherein the positioning rib 22 and positioning recess24 are adapted with a force-fit connection, wherein the force-fitconnection includes an extraction force less than a weight of thepackaging 2.

Clause 28. A pre-packaged injection device 4, or injection devicetraining device, arranged with a positioning recess 24 thereofaccommodating a positioning rib 22 of the packaging 2 of any of clauses1-25 or another embodiment disclosed herein.

Clause 29. The system of any of clauses 19-27 or the pre-packagedinjection device of clause 26 or another embodiment disclosed herein,wherein the injection device comprises a medicament as disclosed herein.

Clause 30. The system of any of clauses 19-27 or 29 or the pre-packagedinjection device clause 26 or another embodiment disclosed herein,wherein the injection device is for use in the treatment or preventionof a disorder as disclosed herein.

Clause 31. Use of the packaging 2 of any of clauses 1-19 or anotherembodiment disclosed herein, for accommodating an injection device or aninjection device training device.

Clause 32. Use of an injection device 4 for accommodating andrestraining the positioning rib 22 of the packaging 2 of any of clauses1-19 or another embodiment disclosed herein.

Clause 33. The injection device of any preceding clause including amedicament as disclosed herein.

Clause 34. An injection device comprising a positioning recess 24adapted to accommodate the positioning rib 22 of the packaging 2 of anyof clauses 1-19 or another embodiment disclosed herein. The injectiondevice may include a medicament as disclosed herein, e.g. arranged in acontainer thereof.

Clause 33. A method of stowing an injection device 4 or injection devicetraining device, in packaging 2. The packaging may be according to anyof clauses 1-32 or another embodiment as disclosed herein, the methodmay include arranging said device with a positioning recess 24, 38thereof arranged within a longitudinal field 15 defined by a handlingrecess 14 of the packaging 2, the handling recess 14 extending laterallyan arranged through a longitudinal wall 6, the longitudinal wall 6forming a longitudinally extending channel 4 to accommodate theinjection device, inserting the aligned device into the channel.

Clause 34. The method of clause 34 or another embodiment disclosedherein, including inserting a positioning rib 22 of the channel 6 of thepackaging 2 into a positioning recess 24 of the device, the positioningrib arranged within a longitudinal field of the handling channel 14.

Clause 35. A method of stiffening injection device packaging 2. Thepackaging may be according to any of clauses 1-34 or another embodimentas disclosed herein, the method may include accommodating a positioningrib 22 of packaging within a positioning recess 24 of an injectiondevice 4, wherein the positioning recess cooperates with the positioningrib to support the positioning rib, the positioning rib arrangedlongitudinally in a channel 6 to accommodate the injection device, thepositioning rib to increase a flexural rigidity longitudinally along alaterally extending handling recess.

Clause 36. A method of extracting an injection device 4, or injectiondevice training device, stowed in packaging 2. The packaging may beaccording to any of clauses 1-34 or another embodiment as disclosedherein, the method may include inserting a digit of a user into alaterally extending handling recess 8, the recess arranged through alongitudinal wall 8, the longitudinal wall 8 forming a longitudinallyextending channel 6 to accommodate said device, the channel comprising alongitudinally extending rib 22 operatively arranged to stiffen thehandling recess. The method may include gripping said device with thedigit and extracting it from the channel.

Clause 37. Packaging 2 for an injection device 4, the packaging mayinclude the packaging of any preceding clause or another embodimentdisclosed herein. The packaging may be arranged to be insertable intocorresponding packaging to a first depth, wherein the packaging andcorresponding packaging have a first orientation, which comprisescorresponding orientation. The first orientation may include thecorresponding packaging with a distal end thereof arranged proximal adistal end of the packaging. The packaging may be arranged to beinsertable into corresponding packaging to a second depth, wherein thepackaging and corresponding packaging have an alternative secondorientation. The second orientation may include the correspondingpackaging with a distal end thereof arranged proximal a proximal end ofthe packaging. The packaging may include a groove 88 forming acorresponding protrusion 96 for insertion into a corresponding groove 88of the corresponding packaging. The protrusion 96 of the packaging maybe insertable in to the groove of the corresponding packaging in thefirst orientation. In the second orientation, a base 98 of the groove 88of the packaging may abut a wall 94 of the corresponding packaging torestrict insertion to the second depth. In the first orientation thebase 98 of the groove 88 of the packaging may restrict insertion depth.

In the claims, any reference signs placed between parentheses shall notbe construed as limiting the claim. The word ‘comprising’ does notexclude the presence of other elements or steps then those listed in aclaim. Furthermore, the terms “a” or “an,” as used herein, are definedas one or more than one. Also, the use of introductory phrases such as“at least one” and “one or more” in the claims should not be construedto imply that the introduction of another claim element by theindefinite articles “a” or “an” limits any particular claim containingsuch introduced claim element to inventions containing only one suchelement, even when the same claim includes the introductory phrases “oneor more” or “at least one” and indefinite articles such as “a” or “an.”The same holds true for the use of definite articles. Unless statedotherwise, terms such as “first” and “second” are used to arbitrarilydistinguish between the elements such terms describe. Thus, these termsare not necessarily intended to indicate temporal or otherprioritization of such elements. The mere fact that certain measures arerecited in mutually different claims does not indicate that acombination of these measures cannot be used to advantage.

Unless otherwise explicitly stated as incompatible, or the physics orotherwise of the embodiments, example or claims prevent such acombination, the features of the foregoing embodiments and examples, andof the following claims may be integrated together in any suitablearrangement, especially ones where there is a beneficial effect in doingso. This is not limited to only any specified benefit, and instead mayarise from an “ex post facto” benefit. This is to say that thecombination of features is not limited by the described forms,particularly the form (e.g. numbering) of the example(s), embodiment(s),or dependency of the claim(s). Moreover, this also applies to the phrase“in one embodiment”, “according to an embodiment” and the like, whichare merely a stylistic form of wording and are not to be construed aslimiting the following features to a separate embodiment to all otherinstances of the same or similar wording. This is to say, a reference to‘an’, ‘one’ or ‘some’ embodiment(s) may be a reference to any one ormore, and/or all embodiments, or combination(s) thereof, disclosed.Also, similarly, the reference to “the” embodiment may not be limited tothe immediately preceding embodiment.

Unless otherwise stated, an object which is said to extend in aparticular direction is to be construed as having a component of adirectional vector that extends in said direction and does on precludethe extension in alternative directions.

The foregoing description of one or more implementations providesillustration and description, but is not intended to be exhaustive or tolimit the scope of the invention to the precise form disclosed.Modifications and variations are possible in light of the aboveteachings or may be acquired from practice of various implementations ofthe present disclosure.

LIST OF REFERENCES

2 Packaging   6, 48 Channel     8, 58 First longitudinal wall       40,60 First face       42, 62 Second face       66 Indentation         70Gripping wall     10 Second longitudinal wall       44 First face      46 Second face       68 Indentation         70 Gripping wall    50 Peripheral longitudinal wall       54 First face       56 Secondface     64 Top adjoining wall     12 Base wall     22 Positioning rib      26 First rib end         76 Proximal lateral wall       28 Secondrib end         79 Distal lateral wall       72 First longitudinal wall      74 Second longitudinal wall       77 Adjoining top wall     78Proximal end wall     80 Distal end wall   14, 82 Handling recess     15Longitudinal field     16 First lateral wall     18 Second lateral wall    20 Adjoining wall       23 Reinforcing rib 4 Injection device   29Body     24, 38 Positioning recess       25 First longitudinal wall      27 Second longitudinal wall       29 Base wall       34 Firstrecess end         31 Proximal lateral wall       36 Second recess end        33 Distal lateral wall       52 label   30 Distal end   32Proximal end     35 End cap   11 Longitudinal axis

The invention claimed is:
 1. A packaging for an injection device, thepackaging comprising: a channel extending longitudinally to accommodatethe injection device, the channel including a first longitudinal wall, asecond longitudinal wall opposing the first longitudinal wall, and abase wall adjoining the first longitudinal wall and the secondlongitudinal wall; a handling recess defined by the first longitudinalwall and the second longitudinal wall; and a positioning rib extendinglongitudinally from a first rib end to a second rib end and protrudingfrom the base wall into the channel for insertion into a positioningrecess of the injection device, wherein the positioning rib is arrangedoffset laterally from the handling recess and extending in alongitudinal field defined by the handling recess, wherein a lateralposition of the positioning rib is central in the channel, and whereinthe first longitudinal wall or the second longitudinal wall comprises anindentation adapted for gripping of the packaging, the indentationextending laterally into the first longitudinal wall or the secondlongitudinal wall.
 2. The packaging of claim 1, wherein the handlingrecess includes a first lateral wall and a second lateral wallinterposed by an adjoining wall, wherein the first rib end is alignedlongitudinally to the first lateral wall or outside of the longitudinalfield defined by the handling recess, and wherein the second rib end isaligned longitudinally to the second lateral wall or outside of thelongitudinal field defined by the handling recess.
 3. The packaging ofclaim 2, wherein the first lateral wall and the second lateral wall ofthe handling recess extend along inclined planes which are truncated bythe adjoining wall.
 4. The packaging of claim 2, wherein the base wallof the channel has a greater depth than the adjoining wall of thehandling recess.
 5. The packaging of claim 1, wherein the positioningrib is a single protrusion.
 6. The packaging of claim 1, wherein thepositioning rib has a lateral width ‘w’ and a depth ‘d’ and the handlingrecess has a depth ‘j’, wherein j is 4-15% of the product of w and d³.7. The packaging of claim 1, wherein a top wall of the positioning ribis concave in the lateral direction.
 8. The packaging of claim 1,wherein the positioning rib is dimensioned with a longitudinal length of38.6 mm ±10% and a lateral width of 5.2 mm ±10%.
 9. The packaging ofclaim 1, wherein the handling recess extends laterally, and thepositioning rib stiffens the handling recess.
 10. The packaging of claim1, wherein the injection device contains at least one of glatirameracetate; adalimumab; an anti-CGRP antibody; reslizumab;follicle-stimulating hormone; or a substance for use in treatment orprevention of a disorder that affects dexterity of a user.
 11. A kitcomprising a packaging and an injection device, wherein the injectiondevice defines a positioning recess and comprises a label, wherein thepackaging comprises: a channel extending longitudinally to accommodatethe injection device, the channel including a longitudinal walladjoining a base wall; a handling recess defined by the longitudinalwall; and a positioning rib extending longitudinally from a first ribend to a second rib end and protruding from the base wall into thechannel, wherein the positioning rib is offset laterally from thehandling recess and extends in a longitudinal field defined by thehandling recess, and wherein a lateral position of the positioning ribis central in the channel, and wherein, when the injection device is inthe channel, said positioning recess accommodates the positioning rib,the label is longitudinally offset from the positioning rib, and thelabel is visible from a planform of the packaging.
 12. The kit of claim11, wherein, when the positioning recess accommodates the positioningrib, the positioning recess of the injection device and a top wall ofthe positioning rib are adapted to form a convex-shaped gap between saidtop wall and the positioning recess.
 13. The kit of claim 11, wherein,when the positioning recess accommodates the positioning rib: a distalend of the injection device is spaced from a distal end wall of thechannel, or a proximal end of the injection device is spaced from aproximal end wall of the channel.
 14. The kit of claim 11, wherein, whenthe positioning recess accommodates the positioning rib, the positioningrecess is contiguous or in abutment with the positioning rib.
 15. Thekit of claim 11, wherein the injection device comprises a furtherpositioning recess longitudinally aligned and opposed the positioningrecess.
 16. The kit of claim 11, wherein the positioning recessaccommodates the positioning rib with a force-fit connection having anextraction force less than a weight of the packaging.
 17. The kit ofclaim 11, wherein the injection device contains at least one ofglatiramer acetate; adalimumab; an anti-CGRP antibody; reslizumab;follicle-stimulating hormone; or a substance for use in treatment orprevention of a disorder that affects dexterity of a user.
 18. Apackaging for an injection device, the packaging comprising: a channelextending longitudinally to accommodate the injection device, thechannel including a longitudinal wall adjoining a base wall; a handlingrecess defined by the longitudinal wall; and a positioning rib extendinglongitudinally from a first rib end to a second rib end and protrudingfrom the base wall into the channel for insertion into a positioningrecess of the injection device, wherein the positioning rib is arrangedoffset laterally from the handling recess and extending in alongitudinal field defined by the handling recess, wherein a lateralposition of the positioning rib is central in the channel, and whereinthe positioning rib has a longitudinal length of 38.6 mm ±10% from thefirst rib end to the second rib end and a lateral width of 5.2 mm ±10%.19. The packaging of claim 18, wherein a top wall of the positioning ribis concave in the lateral direction.
 20. The packaging of claim 18,wherein the handling recess includes a first lateral wall and a secondlateral wall interposed by an adjoining wall, wherein the first rib endis aligned longitudinally to the first lateral wall or outside of thelongitudinal field defined by the handling recess, and wherein thesecond rib end is aligned longitudinally to the second lateral wall oroutside of the longitudinal field defined by the handling recess. 21.The packaging of claim 18, wherein a further longitudinal wall extendscontiguous the longitudinal wall of the channel, and the handling recessis also formed through the further longitudinal wall.
 22. A packagingfor an injection device, the packaging comprising: a channel extendinglongitudinally to accommodate the injection device, the channelincluding a longitudinal wall adjoining a base wall; a handling recessdefined by the longitudinal wall; and a positioning rib extendinglongitudinally from a first rib end to a second rib end and protrudingfrom the base wall into the channel for insertion into a positioningrecess of the injection device, wherein the positioning rib is arrangedoffset laterally from the handling recess and extending in alongitudinal field defined by the handling recess, wherein a lateralposition of the positioning rib is central in the channel, and whereinthe positioning rib has a lateral width ‘w’ and a depth ‘d’ and thehandling recess has a depth ‘j’, wherein j is 4-15% of the product of wand d³.
 23. The packaging of claim 22, wherein a top wall of thepositioning rib is concave in the lateral direction.
 24. The packagingof claim 22, wherein the handling recess includes a first lateral walland a second lateral wall interposed by an adjoining wall, wherein thefirst rib end is aligned longitudinally to the first lateral wall oroutside of the longitudinal field defined by the handling recess, andwherein the second rib end is aligned longitudinally to the secondlateral wall or outside of the longitudinal field defined by thehandling recess.
 25. The packaging of claim 22, wherein a furtherlongitudinal wall extends contiguous the longitudinal wall of thechannel, and the handling recess is also formed through the furtherlongitudinal wall.